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War has erupted across the Imperium! Four spacefaring races struggle for supremacy, launching fleets of starships across the galaxy to battle for control of the most prosperous systems. Only one race will successfully expand, explore, exploit and exterminate their way to victory! pocket Imperium is a 4x Micro game. Players will need to use the opportunities to expand, explore, exploit and exterminate to their best advantage. The timing of when to build fleets, when to explore the stars, and when to invade systems Controlled by opponents will be crucial in their quest to rule the Imperium. What's more, in a crowded galaxy, players must choose wisely when to make alliances to bring down powerful enemies — and when to break those Pacts to critically weaken their former allies! Awards amp; honors 2013 Golden geek best print amp; play board game nominee 2–4 players 30–45 min playing time age: 12+
Supplementary Figure 7. Forest plot of sensitivity and specificity in a trial of proton pump inhibitors.
Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate into the esophagus or beyond, resulting in either troublesome symptoms or complications. GERD is heterogeneous in terms of varied manifestations, test findings, and treatment responsiveness. GERD diagnosis can be established wit ...
Hierarchization of diagnosis according to the Chicago classification version 3.0. Reproduced with permission from Kahrilas et al.1 IRP, integrated relaxation pressure; ULN, upper limit of normal; PEP, panesophageal pressurization; DL, distal latency; EGJ, esophagogastric junction morphology; DCI, distal contractile integral; IEM, ineffective esophageal motility.
Comparison of the width of intercellular space among (A) functional heartburn (FH), (B) non-erosive reflux disease (NERD)/proton pump inhibitor (PPI) responders, (C) NERD/PPI non responders, and width of intercellular spaces in all groups (D). **
Expression of mast cell tryptase in the control, post-operative ileus (POI), and ketotifen groups. (A) The average intensity of the expression of calprotectin was analyzed via MetaMorph microscopy automation. Representative immunohistochemical staining of mast cell tryptase for POI at 3 hours after the operation (POI 3H) (B) and POI at 6 hours after the operation (POI 6H) (C). Bars indicate the mean ± SEM (control group, n = 7; POI group, n = 7; ketotifen group, n = 7). *